Senior Research Associate - Protein Biochemist

About This Role

This Senior Research Associate role focuses on developing and executing workflows for protein expression, purification, characterization, and high-throughput screening within the Protein Engineering team. The position suits an experienced protein biochemist who can independently troubleshoot challenging proteins, develop fit-for-purpose strategies, and collaborate across discovery teams.

Responsibilities

• Develop, optimize, and scale protein expression, purification, characterization, and high-throughput screening workflows for diverse protein engineering candidates
• Design multi-modal chromatography strategies and independently troubleshoot expression, solubility, purification, stability, aggregation, and sample-quality challenges
• Execute biochemical and biophysical characterization, including SDS-PAGE, western blotting, analytical SEC, DLS, protein quantification, and related assays
• Analyze results, identify trends, recommend next steps, and communicate findings through presentations and complete, timely record keeping
• Collaborate across protein engineering, screening, and discovery teams; mentor junior scientists and provide technical guidance
• Evaluate and implement new technologies, instrumentation, and workflows that expand the capabilities of the Protein Engineering team
• Contribute to a collaborative, respectful, and scientifically rigorous team environment
• Follow all company safety policies, protocols, and procedures and actively contribute to maintaining a safe laboratory environment

Requirements

• B.S. in Biochemistry, Chemistry, Molecular Biology, Biotechnology, or a related field with 3+ years of relevant protein purification experience, or a M.S. with 1+ years
• Demonstrated expertise in recombinant protein expression, purification, and characterization across multiple expression systems
• Hands-on experience developing chromatography methods using FPLC systems, protein concentration and buffer exchange, and multiple purification modalities
• Strong proficiency with SDS-PAGE and Western blotting
• Ability to design experiments, troubleshoot complex problems, interpret data, and work independently with strong attention to quality and reproducibility
• Strong critical thinking, communication, and collaboration skills
• Skilled to work effectively both independently and within multidisciplinary teams
• Experience developing robust, reproducible, and scalable workflows and using electronic lab notebooks, data-management platforms, and Microsoft Office

Nice to have:

• Analytical SEC, DLS, or additional biophysical methods

Benefits

• Numerous development opportunities offered to build your skills