About the role
Department Name
392303040 Neuropathology
School/College
Academic Joint Departments
Job Description
The Comba Laboratory in the Department of Pathology, Division of Neuropathology, at the University of Alabama at Birmingham (UAB) is seeking a highly motivated and creative postdoctoral researcher to join our multidisciplinary team investigating the mechanisms of glioblastoma (GBM) progression and therapeutic resistance.
Our research focuses on understanding how interactions between glioma cells and the brain microenvironment drive tumor invasion, recurrence, and treatment resistance. We combine cancer biology, neuroscience, extracellular matrix biology, spatial transcriptomics, advanced imaging, and immunology to identify novel therapeutic strategies for malignant brain tumors.
The successful candidate will have access to a highly collaborative research environment and state-of-the-art technologies, including patient-derived glioblastoma models, orthotopic mouse models, 3D organotypic brain slice cultures, live-cell imaging approaches, multiplex immunofluorescence, RNAscope, spatial transcriptomics (10x Visium HD, Xenium), flow cytometry, and bioinformatics analyses.
The Comba Laboratory collaborates extensively with investigators across the UAB O’Neal Comprehensive Cancer Center, the Department of Neurosurgery, the Department of Pathology, and national and international leaders in neuro-oncology, extracellular matrix biology, neuroscience, and spatial biology.
Applications containing a cover letter and current curriculum vitae should be sent to: Andrea Comba via email: andraecomba@uabmc.edu
Required Qualifications
Candidates should possess a Ph.D., M.D., or equivalent degree in cancer biology, neuroscience, molecular biology, genetics, computational biology, or related biomedical fields. Candidates should have experience with cell culture, animal models, molecular biology, imaging, or computational analysis. Experience with 3D organoids or slices models, confocal imaging and bioinformatics analysis is desirable. We are seeking individuals who are enthusiastic and collaborative.
Interested candidates should submit CV, a cover letter detailing research experience and contact details of three references to: Andrea Comba via email: andraecomba@uabmc.edu
Preferred Qualifications
Posting Detail Information
Posting Number
PF1041P
Open Date
06/25/2026
Close Date
Open Until Filled
Yes
Nondiscrimination Statement
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran’s status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB’s Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
Special Instructions for the Position
Pre-employment Background Check
A pre-employment background check investigation is performed on candidates selected for employment.
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