This role serves as SpyGlass Pharma's first dedicated in-house IT leader, responsible for IT strategy, systems administration, and infrastructure within a Microsoft 365-based environment. The Director will manage the company's managed IT and security services provider and partner with a fractional CISO on cybersecurity strategy. This position suits a hands-on builder with experience in scaling IT infrastructure.
Responsibilities
Lead the design, implementation, and administration of SpyGlass Pharma’s IT infrastructure, including Microsoft 365, Entra ID, Intune, networking, and cloud environment
Own the full lifecycle of enterprise IT systems — configuration, security, maintenance, monitoring, and upgrades — across platforms including Egnyte, NetSuite, MasterControl, Bamboo, Veeva Vault, and iMednet/Medrio
Direct and manage SpyGlass’s outsourced IT and help desk provider, including SLAs, escalation, and ongoing evaluation of outsourcing versus in-house transition
Partner with SpyGlass’s fractional CISO to operationalize cybersecurity, AI governance, and access-control policy
Develop and implement IT policies, standard operating procedures, and governance frameworks that scale with company growth from approximately 90 to 300–500 employees, including support for new office locations
Oversee all aspects of system backup and disaster recovery planning, execution, and testing
Collaborate with business functions to assess IT needs, implement solutions, and support strategic projects
Manage user access, system provisioning, and secure integrations across key business platforms, and build scalable onboarding/offboarding and device-lifecycle processes
Serve as a trusted advisor for IT project management and cross-functional support, ensuring clear documentation, timeline management, and issue resolution
Lead vendor evaluations and manage third-party partnerships related to hardware, software, and IT services, and evaluate and implement new tools and platforms
Build the business case for, and hire, SpyGlass’s first internal IT support/systems team member within the first year, then mentor and guide the team as it grows
Ensure regulatory compliance in IT systems operations, including alignment with 21 CFR Part 11, other relevant GxP requirements, and SOX IT general controls, where applicable
Provide exceptional support and training to end users, maintaining a team-first, service-oriented approach
Requirements
Bachelor’s degree in Information Technology, Computer Science, Engineering, or related discipline preferred; an equivalent combination of professional experience, military technical training, and industry certifications will be considered in lieu of a degree
Minimum of 8–10 years of progressive IT systems experience, including experience operating as a hands-on individual contributor as well as in a leadership capacity
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Prior IT experience within a life sciences, pharma, biotech, or other GxP-regulated company, with working knowledge of 21 CFR Part 11, GAMP 5, and computer system validation
Experience scaling an IT function through a significant headcount inflection point (e.g., helped take a company from roughly 100 to 400+ employees)
Deep, hands-on experience administering Microsoft 365, Entra ID, Intune, and Conditional Access
Experience managing an outsourced MSP or IT vendor relationship, including SLA management and vendor governance
Comfort operating as SpyGlass’s sole IT leader initially — hands-on and strategic simultaneously — with the ability to build the case for and onboard the company’s first internal IT hire within year one
Strong interpersonal skills with the ability to lead cross-functional initiatives and communicate effectively across all levels of the organization
Nice to have:
Experience supporting SOX IT General Controls (ITGCs), including access reviews, change management, and segregation-of-duties controls
Exposure to clinical, quality, or ERP systems (e.g., Veeva, MasterControl, NetSuite, or similar)
Benefits
Annual bonus opportunity
Stock options
Comprehensive health, dental, and vision insurance plans with a variety of plan and coverage options
Generous paid time off, including holidays, vacation days, and personal leave
About the Company
SpyGlass Pharma (NASDAQ: SGP) is focused on improving and preserving the vision of patients living with chronic eye diseases by advancing innovative long-term ophthalmic drug delivery technologies. The company is entering an exciting stage of growth as it advances its lead program, the SpyGlass BIM-IOL, through Phase 3 clinical development.
