Director, Tax Operations

About This Role

Directing tax operations involves managing the company's global tax reporting and compliance functions for the US, reporting to the Head of Tax Operations. The Director is responsible for the operational execution of tax accounting, US compliance, indirect taxes, SOX controls, audits, and their supporting systems and data. This role focuses on modernizing the tax operating model by embedding AI, automation, and analytics into daily tax work, while coordinating with Tax Strategy counterparts on planning and technical positions.

Responsibilities

• Manage ASC 740 tax accounting including provisions, reconciliations, financial statement disclosures, and external audit coordination
• Ensure SOX-compliant internal controls over tax reporting processes, including AI and automation-enabled workflows
• Oversee all U.S. federal, state, and international tax compliance, filings, payments, and audit-ready documentation
• Manage tax credits (R&D, orphan drug), indirect taxes (sales/use, property, excise), and tax audits/examinations
• Monitor and implement regulatory changes including OECD Pillar Two, U.S. CAMT, and international statutory requirements
• Lead tax operations AI strategy by identifying use cases, piloting solutions, and establishing responsible-use guardrails
• Own tax technology platforms, analytics tools, and data initiatives while driving process transformation and team upskilling
• Partner with Tax Strategy and cross-functional stakeholders while leading and developing the Tax Operations team

Requirements

• Bachelor's Degree in Tax, Accounting, Finance, or a related field plus at least 10 years of progressive corporate tax experience (or equivalent combination of education and professional experience) working for or with publicly traded, multinational companies

Nice to have:

• Combination of Big 4 and in-house experience
• Deep expertise in ASC 740, including provisions, uncertain tax positions, financial statement disclosures, and strong U.S. federal and state income tax experience, with exposure to indirect taxes
• Life sciences or biopharmaceutical industry experience
• International and statutory reporting experience (FRS 102, IFRS); Ireland experience a plus
• Familiarity with the OECD global minimum tax (Pillar Two) and the U.S. corporate alternative minimum tax (CAMT)
• Experience leading tax technology, automation, or data-analytics initiatives

Benefits

• Competitive and comprehensive total rewards package which may include: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits

Important Details

• Schedule: full-time
• Work format: four days per week in the Sleepy Hollow, NY office

About the Company

At Regeneron, science and innovation are used to develop life-changing medicines for people with serious diseases. The company is committed to building a workplace with an inclusive culture.