Associate Director, Manufacturing

About This Role

This role anchors day-to-day operations for the Singapore Antibody-Drug Conjugate (ADC) manufacturing buildings, translating strategy into safe, compliant, and dependable performance across shifts. You will lead end-to-end GMP manufacturing execution, ensuring complex operations flow, right-first-time outcomes, and building team capability to meet an ambitious production schedule. The position suits a passionate individual with relevant experience who thrives in dynamic environments and brings a "make-it-happen" attitude.

Responsibilities

• Lead daily and weekly execution of the approved production plan across shifts, setting clear priorities and deploying resources effectively
• Run disciplined critical issue to protect safe batch progression and schedule adherence
• Maintain visible leadership on the floor, coach first line leaders at the point of execution, and reinforce standard work and data-driven behaviors
• Close performance gaps promptly to deliver right-first-time outcomes
• Uphold cGMP, process safety, occupational safety, containment controls, and local requirements
• Ensure hazards and operational risks are understood and controlled before and during execution
• Ensure timely initiation and operational ownership of deviations
• Lead or sponsor structured root cause analysis and deliver effective CAPAs that reduce recurrence and improve control
• Drive manufacturing readiness for assigned systems, areas, and campaigns, including procedures, batch records, training, staffing, line readiness, materials, cleaning, digital workflows, and acceptance of qualified equipment into routine operations
• Coordinate day-to-day delivery with QA, QC, Engineering, Validation, Safety, Supply Chain, MSAT, and project teams
• Resolve issues within delegated authority and call out material risks with clear options and recommendations
• Represent Manufacturing in technical transfer, process validation, and change implementation
• Ensure operational requirements are embedded and teams, documentation, materials, and equipment are ready before execution
• Deploy approved Lean, digital, and responsibly governed AI-enabled solutions
• Use data and structured problem solving to improve flow, reliability, changeover, cycle time, documentation quality, and productivity without compromising GMP or safety
• Establish tier performance management and control execution using agreed metrics across safety, quality, delivery, cost, and people
• Track schedule adherence, right-first-time, deviation recurrence, downtime, cycle time, and changeover performance
• Lead and develop Manufacturing shift leads and team leaders
• Set clear expectations, coach performance, strengthen technical and leadership capability, support succession plans, and foster an inclusive, accountable culture